[WCIR2009]生物钟与糖尿病--P.Grant教授访谈
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专家访谈 综合领域 作者:PeterJ.Grant 来源:未知 2009/12/1 10:00:00    加入收藏
内容概要:《国际糖尿病》:您出色的研究发现胰岛素抵抗和一些与血栓形成有关的因子之间显著相关。胰岛素抵抗的个体凝血-抗凝系统最主要的特征性改变是什么?

    International Diabetes: I see.What steps have been taken in circadian rhythm and understanding the clock?

《国际糖尿病》:我明白了。形成昼夜节律性有哪些步骤呢,以及如何来理解生物钟呢?

    Dr Grant: Well the clock is a very interesting phenomenon because it exists at several levels.  The master block sits in the brain and it is complex series of transcriptional factors which are activated in response to light and variability and sets up an oscillating system which changes your metabolism according to the amount of light there is.So it is switched on when there is light availability and it is switched off when light becomes dark putting your metabolism in time with the light dark cycle.But that master clock also runs a<

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