《国际糖尿病》：目前对肠促胰岛素的关注越来越多，并且对它的研究也越来越深入，然而，其在血管功能方面的有益作用却较少为人所知，您能介绍一下其对血管的益处吗？

    International Diabetes : There has been intensive discussion and increasing popularity regarding incretins however its beneficial effects on vascular functions are lesser known.  Could you discuss those vascular benefits?

    Gerald Reaven教授：好的。现在还不清楚这些复合物是否会随着每天外周胰岛素水平的升高而停止分泌，尤其在血糖中等程度升高的患者中，我认为有一些情况下，可能会产生一些实际上是增加血管方面的严重负面后果。另外如果它们的作用仅仅是降糖和降低胰岛素使用量，那么我们能够预见它们可能具有的益处。

    Dr Reaven:  Well what is not clear is do these compounds end up with increasing day long ambient insulin levels particularly in individuals whose hyperglycemia is modest and in that situation I can conceive a serious of events that might actually increased vascular difficulties.  On the other hand if all they do is lower glucose and lower insulin then you could predict they might have beneficial effects.
 

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